In the past twenty years hundreds of infants and young children have died after being left in vehicles, usually by accident. When turning the vehicle off, drivers of the Titan XD are reminded to check the back seat if they opened the rear door before starting out. The F-150 doesn’t offer a back seat reminder.
To provide maximum traction and stability on all roads, Full-Time Four-Wheel Drive is standard on the Titan XD. But it costs extra on the F-150.
Both the Titan XD and the F-150 have standard driver and passenger frontal airbags, front side-impact airbags, driver and front passenger knee airbags, side-impact head airbags, front seatbelt pretensioners, height adjustable front shoulder belts, plastic fuel tanks, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, lane departure warning systems, blind spot warning systems, rearview cameras, rear cross-path warning, driver alert monitors, available daytime running lights and around view monitors.
The Nissan Titan XD weighs 501 to 2816 pounds more than the Ford F-150. The NHTSA advises that heavier vehicles are much safer in collisions than their significantly lighter counterparts.

